MIPS FUNCTIONAL CATALOGUE 01 METABOLISM 01.01 amino-acid metabolism 01.01.01 amino-acid biosynthesis 01.01.04 regulation of amino-acid metabolism 01.01.07 amino-acid transport 01.01.10 amino-acid degradation 01.01.99 other amino-acid metabolism activities 01.02 nitrogen and sulphur metabolism 01.02.01 nitrogen and sulphur utilization 01.02.04 regulation of nitrogen and sulphur utilization 01.02.07 nitrogen and sulphur transport 01.02.99 other nitrogen and sulphur metabolism activities 01.03 nucleotide metabolism 01.03.01 purine-ribonucleotide metabolism 01.03.04 pyrimidine-ribonucleotide metabolism 01.03.07 deoxyribonucleotide metabolism 01.03.10 metabolism of cyclic and unusual nucleotides 01.03.13 regulation of nucleotide metabolism 01.03.16 polynucleotide degradation 01.03.19 nucleotide transport 01.03.99 other nucleotide-metabolism activities 01.04 phosphate metabolism 01.04.01 phosphate utilization 01.04.04 regulation of phosphate utilization 01.04.07 phosphate transport 01.04.99 other phosphate metabolism activities 01.05 carbohydrate metabolism 01.05.01 carbohydrate utilization 01.05.04 regulation of carbohydrate utilization 01.05.07 carbohydrate transport 01.05.99 other carbohydrate metabolism activities 01.06 lipid, fatty-acid and sterol metabolism 01.06.01 lipid, fatty-acid and sterol biosynthesis 01.06.04 breakdown of lipids and phospholipids 01.06.07 lipid, fatty-acid and sterol utilization 01.06.10 regulation of lipid, fatty-acid and sterol biosynthesis 01.06.13 lipid and fatty-acid transport 01.06.16 lipid and fatty-acid binding 01.06.99 other lipid, fatty-acid and sterol metabolism proteins 01.07 biosynthesis of vitamins, cofactors, and prosthetic groups 01.07.01 metabolism of vitamins, cofactors, and prosthetic groups 01.07.04 utilization of vitamins, cofactors, and prosthetic groups 01.07.07 regulation of vitamins, cofactors, and prosthetic groups 01.07.10 transport of vitamins, cofactors, and prosthetic groups 01.07.99 other vitamin, cofactor, and prosthetic group activities 01.20 secondary metabolism 01.20.01 phenylpropanoids/phenolics metabolism 01.20.02 terpenoids metabolism 01.20.03 alkaloids metabolism 01.20.04 non-protein amino acids metabolism 01.20.05 amines metabolism 01.20.06 glucosinolates metabolism 01.20.99 other secondary metabolism activities 02 ENERGY 02.01 glycolysis 02.04 gluconeogenesis 02.07 pentose-phosphate pathway 02.10 tricarboxylic-acid pathway 02.13 respiration 02.13.01 electron transport proteins 02.13.03 accessory proteins 02.16 fermentation 02.19 metabolism of energy reserves (glycogen, trehalose) 02.22 glyoxylate cycle 02.25 beta-oxidation of fatty acids 02.30 photosynthesis 02.30.01 electron transport proteins 02.13.03 accessory proteins 02.99 other energy generation activities 03 CELL GROWTH, CELL DIVISION AND DNA SYNTHESIS 03.01 cell growth 03.04 budding, cell polarity and filament formation 03.07 pheromone response, mating-type determination, sex-specific proteins 03.10 sporulation and germination 03.13 meiosis 03.16 DNA synthesis and replication 03.19 recombination and DNA repair 03.22 cell cycle control and mitosis 03.22.01 cell cycle check point proteins 03.25 cytokinesis 03.26 growth regulators 03.99 other cell growth, cell division and DNA synthesis activities 04 TRANSCRIPTION 04.01 rRNA transcription 04.01.01 rRNA synthesis 04.01.04 rRNA processing 04.01.99 other rRNA-transcription activities 04.03 tRNA transcription 04.03.01 tRNA synthesis 04.03.03 tRNA processing 04.03.06 tRNA modification 04.03.99 other tRNA-transcription activities 04.05 mRNA transcrition 04.05.01 mRNA synthesis 04.05.01.01 general transcription activities 04.05.01.04 transcriptional control 04.05.01.07 chromatin modification 04.05.03 mRNA processing (splicing) 04.05.05 mRNA processing (5'-end, 3'-end processing and mRNA degradation) 04.05.99 other mRNA-transcription activities 04.07 RNA transport 04.99 other transcription activities 05 PROTEIN SYNTHESIS 05.01 ribosomal proteins 05.04 translation (initiation, elongation and termination) 05.07 translational control 05.10 tRNA-synthetases 05.99 other protein-synthesis activities 06 PROTEIN DESTINATION 06.01 protein folding and stabilization 06.04 protein targeting, sorting and translocation 06.07 protein modification (glycolsylation, acylation, myristylation, palmitylation, farnesylation and processing) 06.10 assembly of protein complexes 06.13 proteolysis 06.13.01 cytoplasmic degradation 06.13.04 lysosomal and vacuolar degradation 06.13.07 other subcellular degradation 06.20 storage proteins 06.99 other protein-destination activities 07 TRANSPORT FACILITATION 07.01 ion channels 07.04 ion transporters 07.04.01 metal ion transporters (Cu, Fe, etc.) 07.04.04 other cation transporters (Na ,K ,Ca ,NH4 ,etc.) 07.04.07 anion transporters (Cl, SO4, PO4, etc.) 07.07 sugar and carbohydrate transporters 07.10 amino-acid transporters 07.13 lipid transporters 07.16 purine and pyrimidine transporters 07.19 allantoin and allantoate transporters 07.22 transport ATPases 07.25 ABC transporters 07.28 drug transporters 07.99 other transport facilitators 08 INTRACELLULAR TRANSPORT 08.01 nuclear transport 08.02 chloroplast transport 08.04 mitochondrial transport 08.07 vesicular transport (Golgi network, etc.) 08.10 peroxisomal transport 08.13 vacuolar transport 08.16 extracellular transport 08.19 cellular import 08.22 cytoskeleton-dependent transport 08.99 other intracellular-transport activities 09 CELLULAR BIOGENESIS (proteins are not localized to the corresponding organelle) 09.01 biogenesis of cell wall 09.02 biogenesis of plasma membrane 09.03 biogenesis of cytoplasm 09.04 biogenesis of cytoskeleton 09.07 biogenesis of endoplasmatic reticulum 09.08 biogenesis of Golgi 09.09 biogenesis of intracellular transport vesicles 09.10 nuclear biogenesis 09.13 biogenesis of chromosome structure 09.16 mitochondrial biogenesis 09.19 peroxisomal biogenesis 09.22 endosomal biogenesis 09.25 vacuolar and lysosomal biogenesis 09.26 chloroplast biogenesis 09.99 other cellular biogenesis activities 10 SIGNAL TRANSDUCTION 10.01 unspecified signal transduction 10.01.01 receptor proteins 10.01.03 second messenger formation 10.01.05 mediator proteins 10.01.07 G-proteins 10.01.09 regulation of G-protein activity 10.01.11 key kinases 10.01.13 key phosphatases 10.01.99 other unspecified signal transduction activities 10.02 morphogenesis 10.02.01 receptor proteins 10.02.03 second messenger formation 10.02.07 G-proteins 10.02.09 regulation of G-protein activity 10.02.11 key kinases 10.02.13 key phosphatases 10.02.99 other morphogenetic activities 10.03 osmosensing 10.03.01 receptor proteins 10.03.05 mediator proteins 10.03.11 key kinases 10.03.13 key phosphatases 10.03.99 other osmosensing activities 10.04 nutritional response pathway 10.04.01 receptor proteins 10.04.03 second messenger formation 10.04.05 mediator proteins 10.04.07 G-proteins 10.04.09 regulation of G-protein activity 10.04.11 key kinases 10.04.13 key phosphatases 10.04.99 other nutritional-response activities 10.05 pheromone response generation 10.05.01 receptor proteins 10.05.07 G-proteins 10.05.09 regulation of G-protein activity 10.05.11 key kinases 10.05.13 key phosphatases 10.05.99 other pheromone response activities 10.99 other signal-transduction activities 11 CELL RESCUE, DEFENSE, CELL DEATH AND AGEING 11.01 stress response 11.04 DNA repair (direct repair, base excision repair and nucleotide excision repair) 11.05 Disease and defense 11.05.01 resistance proteins 11.05.03 defense related proteins 11.07 detoxificaton 11.07.01 detoxification involving cytochrome P450 11.10 cell death 11.11 ageing 11.13 degradation of exogenous polynucleotides 11.99 other cell rescue activities 13 IONIC HOMEOSTASIS 13.01 homeostasis of metal ions 13.04 homeostasis of other ions 30 CELLULAR ORGANIZATION (proteins are localized to the corresponding organelle) 30.01 organization of cell wall 30.02 organization of plasma membrane 30.03 organization of cytoplasm 30.04 organization of cytoskeleton 30.05 organization of centrosome 30.07 organization of endoplasmatic reticulum 30.08 organization of Golgi 30.09 organization of intracellular transport vesicles 30.10 nuclear organization 30.13 organization of chromosome structure 30.16 mitochondrial organization 30.19 peroxisomal organization 30.22 endosomal organization 30.25 vacuolar and lysosomal organization 30.26 chloroplast organization 30.90 extracellular/secretion proteins 30.99 other cellular organization 40 TISSUE SPECIFICITY 40.01 FUNGI 40.01.01 40.02 PLANTS 40.02.01 40.03 MAMMALS 40.03.01 50 DEVELOPMENTAL STAGE 50.01 FUNGI 50.01.01 50.02 PLANTS 50.02.01 50.03 MAMMALS 50.03.01 90 RETROTRANSPOSONS AND PLASMID PROTEINS 90.01 LTR retroelements 90.02 non-LTR retroelements 90.99 other retrotransposons and plasmid proteins 98 CLASSIFICATION NOT YET CLEAR-CUT 99 UNCLASSIFIED PROTEINS